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N-Me-L-Ala-maytansinol Prepared Antibody Conjugated Active Molecules

N-Me-L-Ala-maytansinol Prepared Antibody Conjugated Active Molecules

English name：N-Me-L-Ala-maytansinol
CAS number：77668-69-0
English synonym：
AP3Intermidate1;maytansinol3-(S)-α-N-methylaminopropionate;AP3Intermidate;N-Me-L-Ala-maytansinol;Maytansine,N2'-deacetyl-;Benzoicacid,4-fluoro-,(5-bromo-4-methoxyphenyl)methylester;(1S,2R,3S,5S,6R,16E,1Chemicalbook8E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl(2S)-2-(methylamino)propanoate
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Products Description

 

English name：N-Me-L-Ala-maytansinol

CAS number：77668-69-0

Molecular formulaC32H44ClN3O9

Molecular weight 650.17

EINECS No. 604-604-1

 

Molecular structure:

2 -

 

N-Me-L-Ala-maytansinol properties

 

Boiling point 849.5±65.0 °C(Predicted)

Density 1.31± 0.1g /cm3(Predicted)

Morphological solid

Acidity coefficient (pKa)9.82±0.70(Predicted)

Color White to beige

 

The use and synthesis method of N-Me-L-Ala-maytansinol

 

Bioactive N-Me-L-a L-a-Maytansinol is a hydrophobic, cell-permeable payload for the preparation of antibody-coupled drugs (ADCs).
Target point
Maytansinoids

 

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