Ferric Carboxymaltose Iron Deficiency Anemia Drugs

Ferric Carboxymaltose Iron Deficiency Anemia Drugs

English name:Ferric carboxymaltose
CAS number:9007-72-1
Another name: Ferinject ;Ferric carboxymaltose; Injectafer; Iron Dextri-Maltose ;Ferric Carboxymaltos ;Ferric carboxymahose; Injectafer USP/EP/BP; Ferric Carboxymaltose Injectafer
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Products Description

 

English name:Ferric carboxymaltose

CAS number:9007-72-1

Molecular formula: C39H63FeO39

Molecular weight: 1211.73912

EINECS number: 813-933-0

 

Related category

Pharmaceutical raw materials; Inventory; Medical raw materials; Pharmaceutical raw materials; Chemical reagent; Organic chemical raw materials; Organic compounds; API; 9007-72-1

Mol file:9007-72-1.mol

 

Structural formula:

1

 

Iron properties of carboxymaltose

InChIKey:CRTIFGUDJMSNSV-SJEGEKMXNA-K

 

Application and synthesis of carboxyl maltose iron

 

Use

Carboxymaltose iron is a new type of intravenous iron agent. It is a complex (codenamed "VIT-45") formed by the encircle of the trivalent polynuclear iron core (β-FeOOH) by carboxyl maltodextrin (i.e. the oxidation product of maltodextrin). This core-shell structure can stabilize the iron complex and control the release of iron. Therefore, it can prevent the toxic oxides produced by the saturation of ferric transporters and ferric Chemicalbook proteins due to high blood iron concentration. Carboxymaltose iron contains high iron content (24-32%, the iron content in its injection is 47.5-52.5mg/mL, and 500-1500mg iron can be quickly injected within 15min), with fewer times of administration and good iron supplementation effect, which greatly improves patients' compliance. It is a good intravenous iron supplement.

 

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