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Rocuronium Bromide Intermediate Neuromuscular Blocking Agent

Rocuronium Bromide Intermediate Neuromuscular Blocking Agent

English name：Rocuronium bromide intermediate
CAS number：119302-24-8
English synonym：
2-β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5a-androstan-3a,17β-diol-17-acetate;(2B,3A,5A,16B,17B)-17-ACETOXY-3-HYDROXY-2-(4-MORPHOLINYL)-16-(1-PYRROLIDINYL)ANDROSTANE;（2，3，5，16，17）-17-acetoxy-3-hydroxy-2-（4-morpholinyl）-16-（1-pyrrolidinyl）androstane;(2b,3a,5a,16b,17b)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)-androstane-3,17-diol 17-acetate;2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-acetate;2beta-(4-Morpholinyl)-16beta-(1-pyrrolidinyl)-5alpha-androstane-3alpha,17beta-diol 17-acetate;(2b,3a,5a,16b,17b)-17-Acetoxy-3-hydroxy-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane (2b,3a,5a,16b,17b)-1;RocuroniuM BroMide InterMediate VIII
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Products Description

 

English name：Rocuronium bromide intermediate
CAS number：119302-24-8
Molecular formula：C29H48N2O4
Molecular weight 488.7
EINECS number 601-596-0
Related categories:Pharmaceutical intermediates; organic raw materials; intermediates; reference impurities; rocuronium related intermediates; impurity standard; pharmaceutical raw materials; reference-impurity control; rocuronium impurities; Intermediates

 

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Rocuronium bromide intermediate properties

 

Melting point：152-156°C

Boiling point：574.1±50.0 °C(Predicted)

Density：1.17

vapour pressure：0Pa at 25℃

Solubility is soluble in chloroform (minor), DMSO (mild, heated), methanol (mild)

condition of storage：under inert gas (nitrogen or Argon) at 2-8°C

acidity coefficient：(pKa)14.85±0.70(Predicted)

Morphological solid

White to light brown in color

LogP3.9 at 22℃ and pH12

 

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